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Glossary of life science terms

Life science uses various terms and concepts to explain the functions and processes of living organisms. Use this glossary to understand any unfamiliar terminology you come across.

To help you navigate, the glossary terms have been separated based on the topic they fall under. If you are unsure, just hit CTRL+F to find the term you are looking for!

Structure and function of cells

The table outlines the definitions for key terms in Structure and function of cells.

Term Definition
active transport a transport process that requires energy in which molecules move from a region of lower concentration to an area of higher concentration
anaphase the stage of mitosis in which sister chromatids are pulled apart by spindle fibres to opposide sides of the cell
antiporter a type of carrier protein that transports two molecules across the cell membrane at a time, in opposite directions
binary fission the process by which a single parent reproduces to form offspring
cell cycle a series of events that a cell goes through as it grows and divides
cell membrane a flexible phospholipid bilayer with embedded proteins and other molecules; also known as the plasma membrane
cell theory the cell is the most basic unit of life, all living organisms are composed of one or more cells and all cells arise only from pre-existing cells
cell wall the rigid outer layer that provides structural support and protection for plant cells
cellular respiration the chemical process that converts glucose and oxygen into energy in the form of ATP for the cell to function
centrosome structures found near the cell nucleus that are important for cell division
chlorophyll the green pigment that captures light energy
chloroplast the organelle in which photosynthesis occurs
chromatin a complex made of DNA and proteins
cisternae stacked membrane structures that make up the Golgi apparatus
cristae the structures that the inner membrane of the mitochondria are folded into
cytokinesis the stage after mitosis in which the cell's cytoplasm divides to form two distinct daughter cells
cytoplasm the gel-like filling inside a cell
cytoskeleton a network of protein fibres that help organiste the contents of a cell
endoplasmic reticulum a network of membranes involved in protein and lipid synthesis; abbreviated to ER
eukaryotic cell a cell that has a well-defined nucleus and membrane-bound organelles
facilitated diffusion a passive transport process in which molecules move from an area of higher concentration to an area of lower concentration with the help of special proteins
fluid mosaic model states that the cell membrane is a dynamic, flexible, semi-permeable phospholipid bilayer with embedded proteins
G1 stage the stage of interphase in which the cell grows and carries out regular metabolic functions
G2 stage the stage of interphase in which the cell continues to grow and produce what it needs for mitosis
Golgi apparatus the organelle that modifies, sorts and packages proteins and lipids for transport
grana stacks of thylakoids
interphase the phase in which the cell grows and its genetic material is replicated
lumen channel
lysosome the organelle that contains digestive enzymes to break down excess or old cell parts, food particles and invading viruses or bacteria
matrix (in mitochondria) the space inside the cristae
metaphase the stage of mitosis in which the chromosomes align at the equator of the cell
mitochondria the powerhouse of the cell that produces energy in the form of ATP for the cell to function
mitosis the process by which a cell divides into two identical daughter cells
multicellular an organism consisting of multiple cells
nuclear envelope a double membrane that surrounds the nucleus
nucleolus a dense area within the nucleus where the ribosomal RNA is found
nucleoplasm the gel-like filling inside a nucleus
nucleus the control centre of the cell that houses the cell's genetic material
organelle a specialised structure in eukaryotic cells that performs a distinct function
photosynthesis the chemical process that converts carbon dioxide, water and energy from sunlight into oxygen and glucose
prokaryotic cell a cell that lacks a cell nucleus and membrane-bound organelles
prophase the stage of mitosis in which the chromosomes condense and the nuclear envelope begins to dissolve
rate of diffusion the amount of material that is transported over a specific amount of time
ribosome the organelle that reads instructions from the messenger RNA to assemble proteins
rough endoplasmic reticulum endoplasmic reticulum with ribosomes attached; involved in protein folding and modification
S stage the stage of interphase in which DNA replication occurs
simple diffusion a passive transport process in which molecules move from an area of higher concentration to an area of lower concentration
smooth endoplasmic reticulum endoplasmic reticulum with no ribosomes attached; involved in lipid synthesis and detoxification
stoma the gel-like fluid surrounding the grana
surface area the total area of the cell's outer membrane
surface area to volume ratio a measure that compares the size of a cell's surface to its volume
symporter a type of carrier protein that transports two molecules across the cell membrane at a time, in one direction
telophase the stage of mitosis in which the nuclear envelope reforms around the separated chromosomes and they recondense
thylakoid a membrane in the chloroplast
unicellular an organism consisting of a single cell
uniporter a type of carrier protein that transports one molecule across the cell membrane in one direction
vacuole a storage organelle that stores water, nutrients and waste products in animal cells, and nutrients and waste products in animal cells
vesicle a small compartment into which molecules can be packaged into for transport
volume the amount of space inside the cell

Molecular biology

The table outlines the definitions for key terms in Molecular biology.

Term Definition
5' capping a post-transcriptional modification that involves adding a cap to the 5' end of the mRNA
acetylation the process in which an acetyl group is added
active site the site on an enzyme in which the substrates bind
aminoacyl site the A site of the tRNA where the tRNA with the correct anticodon binds
anticodon a complementary codon to the sense codon
carbohydrate a macromolecule made up of simple sugar monomers
catalyst something that speeds up a chemical reaction
central dogma a fundamental theory in molecular biology that describes the flow of genetic material
centromere the region of a chromatid in which the short and long arm meet
chromatid the structure of a chromosome which has a short arm and a long arm
chromatin a fibre of coiled solenoids
chromosome a condensed structure formed from the packaging and coiling of DNA
codon a set of three nucleotides that corresponds to an amino acid
competitive inhibitor a molecule that binds to the active site of an enzyme and blocks its natural substrate from binding
complementary base pairing the tendency for adenine to pair with thymine, and cytosine to pair with guanine
condensation a reaction in which two molecules come together and react to form one new molecule and release one water molecule
conformational change a change in the 3D structure of a molecule
denaturation a permanent change in the enzyme's structure that causes it to lose its ability to catalyse reactions
deoxyribonucleic acid a nucleic acid that carries the genetic instructions for the cell
enzyme a protein that speeds up chemical reactions
exit site the E site of the tRNA where the tRNA breaks away from the amino acid
glycosylation the process in which a sugar molecule is added
histone packaging proteins that bind to DNA
inactive having low activity
induced fit model states that an enzyme's active site changes shape slightly to bind substrates
initiation factor a protein that helps the mRNA template bind to the ribosome
initiator tRNA the tRNA that recognises the start codon
lipid a hydrophobic macromolecule involved in energy storage
lock-and-key model states that an enzyme's active site is rigid and specifically matches the shape of its substrates
macromolecule a large, complex molecule that is essential for life
methylation the process in which a methyl group is added
monosaccharide a simple monomer of sugar
mRNA messenger RNA that acts as a template for protein production
non-competitive inhibitor a molecule that binds to a different part of an enzyme and causes a conformational change that reduces it activity
nonsense codon a codon that does not correspond to an amino acid
nucleic acid a macromolecule that stores genetic information
nucleosome a section of DNA that is wrapped around a cluster of eight histones
nucleotide a simple monomer of nucleic acids; composed of a nitrogenous base, sugar and phosphate group
peptide bond the bond that links amino acids
peptidyl site the P site fo the tRNA where the amino acid forms a peptide bond with the previous amino acid in the peptide chain
peptidyl transferase an enzyme that helps join amino acids together
phosphodiester bond a bond that links nucleotides
phosphorylation the process in which a phosphate group is added
polyadenylation a post-transcriptional modification that involves adding a poly-A tail to the mRNA
pre-mRNA the product of transcription
primary structure the linear sequence of amino acids linked by peptide bonds
promoter region the region of the DNA that initiates transcription
protein a chain of amino acids
quaternary structure the arrangement of multiple protein subunits into a more complex structure
ribonucleic acid a nucleic acid that plays a role in translating DNA into proteins
RNA polymerase an enzyme that binds to a region of the DNA to start transcription
secondary structure the alpha helices or beta pleated sheets formed by hydrogen bonding between amino acid side chains
sense codon a codon that corresponds to an amino acid
solenoid a coiled spiral of nucleosomes
splicing a post-transcriptional modification that involves cutting introns out of the mRNA and rejoining exons together
start codon the codon AUG that corresponds to the amino acid methionine and also signals that start of translation
stop signal the region of the DNA that terminates transcription
substrate a molecule that binds to an enzyme
tertiary structure the overall 3D shape of a single protein molecule created by bonds between amino acid side chains
transcription the process in which a specific segment of DNA is copied into mRNA
translation the process in which an mRNA template is used to form a protein
tRNA transfer RNA that binds the mRNA template and reads it to form a protein
ubiquitination the process in which a ubiquitin molecule is added
uncompetitive inhibitor a molecule that binds to the enzyme–substrate complex and prevents the product from being released

Genetics

The table outlines the definitions for key terms in Genetics.

Term Definition
activator a regulatory protein that activates transcription
allele different version of a gene
autosomal dominant trait an autosomal trait that requires only one dominant allele for the trait to be expressed
autosomal recessive trait an autosomal trait that requires two copies of the recessive allele for the trait to be expressed
autosomal trait a genetic characteristic determined by genes located on the 22 pairs of autosomes
autosome a non-sex chromosome
carrier an individual that has the allele for the gene but does not express it
cell reproduction the division of cells to create new cells
constitutive gene a gene that is expressed at all times because it is continually being transcribed
cross breeding two organisms together to produce offspring
crossing over the process by which genetic material is exchanged between chromosomes; also called recombination
diploid a cell with two sets of chromosomes
DNA ligase an enzyme that joins together Okazaki fragments
DNA replication the process by which a cell makes an exact copy of its DNA before cell divsiion
dominant trait a trait that will show if one copy of the dominant allele is present
enhancer a region of the DNA where activators bind to increase transcription levels of the gene
facultative gene a gene that is expressed only when it is needed
gamete sex cells like sperm and eggs
gene a sequence of DNA that code for a protein
gene expression the process by which genes are used to produce proteins
gene regulation the process of controlling when and how much of a gene is expressed
genome an organism's entire set of DNA
genotype the allele specific to an individual
haploid a cell with a single set of chromosomes
helicase an enzyme that unwinds the DNA double helix
heterozygous a genotype consisting of two different alleles
homozygous a genotype consisting of two identical alleles
housekeeping gene a type of constitutive gene that is expressed at stable levels
karyotype a visual representation of an organism's complete set of chromosomes
lagging strand the strand of DNA that points away from the replication fork during DNA replication
law of dominance states that when there are two alleles of a gene, one can be dominant and hide the other
law of independent assortment states that alleles for different traits are distributed to gametes independently of one another
law of segregation states that during the formation of gametes, the two alleles of each trait separate so that each gamete receives only one allele
leading strand the strand of DNA that points towards the replication fork during DNA replication
meiosis a type of cell division that produces sex cells
meiosis I the first round of division during meiosis to produce two diploid daughter cells
meiosis II the second round of division during meiosis to produce four haploid daughter cells
Mendel's laws the principles of inheritance developed by Gregor Mendel
Okazaki fragment a short segment of DNA that is replicated from the lagging strand/td>
pedigree a chart that shows how a trait is passed down generations
phenotype a physical trait
promotor a region of the DNA where RNA polymerase binds to start transcription
Punnett square a diagram used to predict the genetic outcomes of a cross
recessive trait a trait that will show only if two copies of the recessive allele are present
recombination the process by which genetic material is exchanged between chromosomes; also called crossing over
replication fork where two single strands of DNA are exposed during DNA replication
repressor a regulatory protein that blocks transcription
sex chromosome an X or Y chromosome
sex-linked trait a genetic characteristic determined by genes located on the sex chromosomes
silencer a region of the DNA where repressors bind to reduce transcription levels of the gene
X-linked dominant trait a sex-linked trait that is caused by dominant alleles on the X chromosome
X-linked recessive trait a sex-linked trait that is caused by recessive alleles on the X chromosome
Y-linked trait a sex-linked trait that is associated with genes on the Y chromosome

Human body systems

The table outlines the definitions for key terms in Human body systems.

Term Definition
absorption the process through which nutrients are transported from the digestive system into the bloodstream
action potential a series of voltage changes across a cell membrane
adenosine triphosphate the body's energy currency
aerobic respiration a process in which energy (in the form of ATP) is produced in abundant oxygen
afferent neurone neurones that carry information from sensory organs to the central nervous system; also called sensory neurones
alveolus a balloon-like structure covered in blood vessels where gas exchange occurs
anaerobic respiration a process in which energy (in the form of ATP) is produed in the low oxygen conditions
anus the end of the digestive tract; an opening through which faeces is removed
aorta the largest artery in the body
artery a blood vessel that transports blood away from the heart to the body's tissues
atrium an upper chamber in the heart
autonomic nervous system the division of the peripheral nervous system that controls involuntary movements
biconcave curved inwards on both sides
bile a digestive fluid produced by the liver that helps break down fats
bile duct a tube that connects the liver and gallbladder to the small intestine
biliary tract the network of tubes and associated organs that make and transport bile from the liver to the small intestine
bladder a muscular sac that stores urine
blood the fluid that delivers nutrients and oxygen to the body's cells
blood vessel a tube that carries blood throughout the body
bolus a mass of food and saliva
bone a strong structure that acts as the framework for the skeleton
bone marrow soft tissue found in spongy bone
brain the command centre for the body
brainstem the structure that connects the brain to the spinal cord
bronchi the branches from the trachea that lead to the lungs
bronchiole the next branch of the bronchi
bronchus a single bronchi
capillary a tiny blood vessel where gas exchange occurs between the blood and body's tissues
capillary bed a network of capillaries where gas exchange occurs
cardiac muscle a type of muscle found in the walls of the heart
cardiovascular system the body system that transports blood, oxygen and nutrients around the body; also called the circulatory system
cartilage a flexible tissue that covers the ends of bones to cushion joints
cartilage a strong connective tissue
cellular respiration the process by which glucose is converted to energy in the form of adenosine triphosphate (ATP)
central nervous system the main control centre of the body; includes the brain and spinal cord
cerebellum the back part of the brain; responsible for coordination and balance
cerebrum the largest part of the brain; responsible for higher thinking processes and voluntary movement
chemical digestion the chemical breakdown of food caused by enzymes and acids
chondrocyte a cartilage cell
chyme the semi-liquid mixture that forms when food is broken down in the stomach
circulatory system the body system that transports blood, oxygen and nutrients around the body; also called the cardiovascular system
compact bone the dense outer layer of bone
defecation the process of removing waste from the body through the anus
depolarisation the process by which the membrane potential gets closer to 0
diaphragm a large dome-shaped muscle found at the base of the ribcage
digestion the process by which the body breaks down food into smaller components
digestive system the body system responsible for breaking down food into a form that the body can use for energy
digestive tract the long tube and associated organs that start at the mouth and end at the anus; also called the alimetary tract or gastrointestinal tract
duodenum the first part of the small intestine, where most of the chemical digestion occurs
ear a sensory organ that detects sound and lets us hear
effector the target tissue
efferent neurone neurones that send information from the central nervous system to the muscles and glands; also called motor neurones
elastic cartilage a type of cartilage that provides strength and elasticity/flexibility
endocrine gland an organ that produces hormones
endocrine system the body system that produces hormones; also called the hormonal system
erythrocyte a type of blood cell that carries oxygen; also called a red blood cell
excretion the process of removing waste from the body
excretory system the body system that removes waste from the body in the form of urine; also known as the urinary or renal system
eye a sensory organ that detects light and lets us see
faeces solid waste produced by the digestive system
fibre a single thread
fibrocartilage a type of cartilage that provides support and absorbs shock
filtrate a liquid that has passed through a filter
filtration (in excretion) the process by which waste products, excess water and unwanted small molecules are passively filtered out of the blood and into the kidney tubule
ganglia clusters of neurone cell bodies
gas exchange the process through which oxygen moves from the lungs into the bloodstream, and waste gases like carbon dioxide move from the bloodstream to the lungs
gastric juice a complex acidic mixture of water, hydrochloric acid and digestive enzymes
glomerulus a tiny network of capillaries inside the nephron
glucagon a hormone produced by the pancreas that raises blood glucose levels
gluconeogenesis the process by which new glucose is formed in the liver
glycogenesis the process by which glucose is converted to glycogen for storage
glyconeogenesis the process by which glucagon is broken down into glucose for use
heart a muscular organ that pumps blood throughout the body
homeostasis the maintenance of a stable internal environment despite external changes
hormone a chemical substance produced by an endocrine gland that is used to communicate to different parts of the body
hyaline cartilage a type of cartilage that is found on many joint surfaces to reduce friction
hyperpolarised when the membrane potential is more negative that its resting potential
hypothalamus a small structure in the brain that bridges the nervous and endocrine system; it helps regulate body temperature, hunger, thirst and emotions
hypoxyapatite a mineral composed of calcium phosphate that makes up a large amount of bone
ileum the third part of the small intestine, where vitamin B12, bile salts and any remaining nutrients are absorbed
inert non-reactive
ingestion the process of taking food into the mouth
insulin a hormone produced by the pancreas that lowers blood glucose levels
intercalated disc a specialised structure found between cardiac muscle cells
intercostal muscle a small muscle found between the ribs
interneurone neurones that link sensory and motor neurones with the centra nervous system
jejunum the second part of the small intestine, where most of the nutrient absorption occurs
joint a region where two bones meet
kidney a bean-shaped organ that filters waste from the blood
large intestine the part of the digestive system between the small intestine and the anus; also called the colon
layrnx the voice box
leukocyte a type of blood cell in the immune system that helps the body fight infection and disease; also called a white blood cell
ligament a strong band of tissue that holds bones together
liver a metabolic organ that has a range of important functions in the body, like detoxification through filtration of blood and assisting in digestion
lobe a division of an organ
locomotor system the body system that includes the bones, muscles, tendons and ligaments in the body; also called the musculoskeletal system
lung a spongy, air-filled organ where gas exchange occurs
mechanical digestion the physical breakdown of food caused by forces of motion
medulla oblongata the lower part of the brainstem that regulates unconscious processes like heartbeat and breathing
membrane potential the difference in charge between the inside and outside of the cell
microfibril a fine fibre
midbrain the top part of the brainstem that controls eye movement and visual and auditory processing
motor neurone neurones that send information from the central nervous system to the muscles and glands; also called efferent neurones
muscular system the body system that provides support and facilitates movement
musculoskeletal system the body system that includes the bones, muscles, tendons and ligaments in the body; also called the locomotor system
nasal cavity the space inside the nose through which most of the air filters through on the way into and out of the body
negative feedback loop a mechanism for regulating internal body conditions where the biological reaction reverses the change caused by a stimulus
nephron a filtration unit inside the kidney
nerve fibre a bundle of neurones
nerve impulse an electrical signal that travels along a neurone
nervous system the body system that controls the body by processing information and sending signals
neurone a specialised cell that sends and receives electrical signals; also called a neuron or nerve cell
neurotransmitter a chemical substance that neurones use to communicate with sensory organs, muscles, glands and other neurones
nose a sensory organ that detects smells and lets us smell
nostrils the entry points to the nasal cavity
oesophagus the tube in the throat that connects the mouth to the stomach
oral cavity the mouth
pancreas the organ that produces digestive enzymes, and hormones like insulin and glucagon
parasympathetic nervous system the divison of the autonomic nervous system that plays a role in the "rest-and-digest" response
periosteum a thin membrane that covers the surface of bone
peripheral nervous system the system that helps the central nervous system communicate with the rest of the body
peristalsis rhythmic smooth muscle contractions that move food through the digestive system
pharynx the section of the respiratory tract that connects the nasal and oral cavities to the larynx and oesophagus; also called the throat
pituitary gland a small structure that sits below the hypothalamus and controls many endocrine glands; also called the master gland
plasma (in blood) the biggest component of blood consisting of water, proteins and other solutes
platelet a small cell fragment involved in blood clotting; also called a thrombocyte
pons the middle part of the brainstem that regulates sleep–wake cycles, breathing and facial expressions
positive feedback loop a mechanism for regulating internal body conditions where the biological reaction amplifies the change caused by a stimulus
post-synaptic neurone the neurone receiving neurotransmitters
pre-synaptic neurone the neurone that releases neurotransmitters into a gap
propulsion the process of moving food through the digestive tract
pulmonary circulation the part of the circulatory system where blood is transported between the heart and lungs
reabsorption (in excretion) the process by which essential nutrients and water are returned to the blood from the kidney tubule
rectum where faeces is stored until it is ready for removal
red blood cell a type of blood cell that carries oxygen; also called an erythrocyte
reflex arc a nerve pathway involved in reflex actions
repolarisation the process by which the membrane potential returns to its resting potential
respiratory system the body system that brings oxygen into the body and removes waste gases
respiratory tract the pathway through which air travels into and out of the body
saliva a fluid produced in the mouth that moistens the food
salivary gland an organ that produces saliva
secretion (in excretion) the process by which additional waste products and toxins are actively transported from the blood into the kidney tubule
sensor something that detects stimuli
sensory neurone neurones that carry information from sensory organs to the central nervous system; also called afferent neurones
sensory organ an organ that detects stimuli from the environment
sinoatrial node the heart's natural pacemaker that is responsible for regulating heartbeat
skeletal muscle a type of muscle that is attached to bones
skeletal system the body system that gives the body support and shape, protecting the internal organs
skeleton the structural frame of the body
skin a sensory organ that detects touch, temperature and pain
small intestine the part of the digestive tract between the stomach and the large intestine, composed of the duodenum, jejunum and ileum; where most of the nutrient absorption occurs
smooth muscle a type of muscle that lines some organs, like the stomach, intestine and blood vessels
somatic nervous system the division of the peripheral nervous system that controls voluntary movements
sphincter a ring of muscle at the end of a tube that controls the passage of substances into or out of the tube
spinal cord the tube of nerve fibres that extends from the brain to the lower back
spongy bone the lighter, porous outer layer of bone
stomach the muscular, hollow organ that receives food from the oesophagus
striated organised in parallel streaks
sympathetic nervous system the division of the autonomic nervous system that plays a role in the "fight-or-flight" response
synapse the gap between a neurone and what it is communicating with
synovial fluid the liquid substance inside a joint that helps it move smoothly
systemic circulation the part of the circulatory system where blood is transported between the heart and the rest of the body
tendon a collagen fibre that connects bones to skeletal muscle
thermoregulation the regulation of internal body temperature
thrombocyte a small cell fragment involved in blood clotting; also called a platelet
tongue a sensory organ that detects taste
trachea a sturdy, cartilage-lined tube that connects the layrnx to the bronchi; also called the windpipe
tubule a small tube
ureter a thin tube that connects the kidneys to the bladder
urethra a tube that carries urine from the bladder out of the body during urination
urinary system the body system that removes waste from the body in the form of urine; also known as the excretory or renal system
urinary tract the pathway through which urine is formed and removed from the body
urination the process of removing urine from the body
urine a yellowish liquid waste formed through kidney filtration
valve a structure that controls the flow of a fluid
vasoconstriction the narrowing of blood vessels
vasodilation the widening of blood vessels
vein a blood vessel that transports blood back to the heart from the body's tissues
vena cava the largest vein in the body
ventricle a lower chamber in the heart
vertebral column the chain of bones that protect the spinal cord
vesicle a capsule containing neurotransmitters
villi tiny finger-like projections that help increase surface area
voice box the structure that houses the vocal cords and connects the pharynx to the trachea
white blood cell a type of blood cell in the immune system that helps the body fight infection and disease; also called a leukocyte